Systematic Literature Review of DPP-4 Inhibitors in Patients with Type 2 Diabetes Mellitus and Renal Impairment

Diabetes Therapy, 2016 09; 7(3): 439-454. e-pub ahead of print 2016/08/10; doi: 10.1007/s13300-016-0189-4

Dipeptidyl peptidase-4 (DPP-4) inhibitors are widely used in the management of patients with type 2 diabetes mellitus (T2DM) and renal impairment (RI). A systematic literature review was performed to compare the efficacy and safety of DPP-4 inhibitors in patients with T2DM and RI.


Thomas MC, Paldanius PM, Ayyagari R, Ong SH, Groop PH