Changes in Practice Patterns of Clopidogrel in Combination with Proton Pump Inhibitors after an FDA Safety Communication

PLoS One, 2016 01; 11(1): e0145504

In 2009, the FDA issued a warning that omeprazole--a proton pump inhibitor (PPI)--reduces the antithrombotic effect of clopidogrel by almost half when taken concomitantly. This study aims to analyze the impact of the FDA Safety Communications on prescribing clopidogrel together with PPIs.

View abstract

Authors

Guerin A, Mody R, Carter V, Ayas C, Patel H, Lasch K, Wu E.