Nicolae Done
Boston
Education
Ph.D., health economics and policy, Johns Hopkins University; A.B., biochemical sciences, Harvard College
Summary of Experience
Dr. Done is a health economist with expertise in statistical and machine learning methodologies, which he applies to the study of a wide range of clinical and economic outcomes in health care. He has led and implemented analyses across the entire product lifecycle, from early-phase clinical trials to post-market real-world evidence (RWE) generation. He has experience in disease areas such as cardiology, neurology, hematology, infectious diseases and vaccines, dermatology, rheumatology, and rare genetic disorders. In his work, Dr. Done uses data from administrative claims, electronic health records, clinical trials, surveys, medical chart reviews, and the medical literature. His research encompasses a variety of study types, including policy evaluations, direct and indirect treatment comparisons, predictive analytics, risk adjustment and simulation, individualized medicine, disease epidemiology, burden of illness, disease treatment patterns, comparative-effectiveness research, systematic literature reviews, and economic modeling. Dr. Done’s research has been used to inform health care payer and delivery system policy, both in the US and globally; published in peer-reviewed journals; and presented at numerous clinical and economic research conferences. Prior to joining Analysis Group, Dr. Done was a research fellow at Boston University and a health economist at the Veterans Health Administration.
Selected Publishing
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Trends in Prevalence and Incidence of Alopecia Areata, Alopecia Totalis, and Alopecia Universalis Among Adults and Children in a US Employer-Sponsored Insured Population
JAMA Dermatology, 2023
2023Mostaghimi A, Gao W, Ray M, Bartolome L, Wang T, Carley C, Done N, Swallow E
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Long-term treatment effects of inotersen on health-related quality of life in patients with hATTR amyloidosis with polyneuropathy: Analysis of the open-label extension of the NEURO-TTR trial
Muscle & Nerve, 2022
2022Karam C, Brown D, Yang M, Done N, Zhu JJ, Greatsinger A, Bozas A, Vera-Llonch M, Signorovitch J
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Factors associated with increased health-related quality-of-life benefits in hereditary transthyretin amyloidosis polyneuropathy patients treated with inotersen
Muscle & Nerve, 2022
2022Karam C, Brown D, Yang M, Done N, Dieye I, Bozas A, Vera-Llonch M, Signorovitch J
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Incidence of invasive pneumococcal disease in children with commercial insurance or Medicaid coverage in the United States before and after the introduction of 7- and 13-valent pneumococcal conjugate vaccines during 1998-2018
BMC Public Health, 2022
2022Hu T, Song Y, Done N, Liu Q, Sarpong EM, Lemus-Wirtz E, Signorovitch J, Mohanty S, Weiss T
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Healthcare Utilization and Costs Among US Adolescents With Alopecia Areata
Journal of Health Economics and Outcomes Research, 2022
2022Ray M, Swallow E, Gandhi K, Carley C, Sikirica V, Wang T, Done N, Signorovitch J, Mostaghimi A